MnTnHex-2-PyP⁵⁺, Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways

Tumor migration and invasion induced by the epithelial-to-mesenchymal transition (EMT) are prerequisites for metastasis. Here, we investigated the inhibitory effect of a mimic of superoxide dismutase (SOD), cationic Mn(III) <i>ortho</i>-substituted <i>N</i>-n-hexylpyridylporphyrin (MnTnHex-2-PyP<sup...

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Bibliografske podrobnosti

Principais autores:	Sung-Won Shin, Changhoon Choi, Hakyoung Kim, Yeeun Kim, Sohee Park, Shin-Yeong Kim, Ines Batinic-Haberle, Won Park
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-11-01
Serija:	Antioxidants
Teme:	manganese porphyrin MnTnHex-2-PyP<sup>5+</sup> SOD mimics radiation therapy metastasis NRF2
Online dostop:	https://www.mdpi.com/2076-3921/10/11/1769
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