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Evaluation of immune protection of a multi-antigenic DNA vaccine encoding TgROP6 and TgMIC12 against Toxoplasma gondii infection

IntroductionToxoplasma gondii infection causes severe congenital disease and abortion in humans and animals. This study evaluated a novel multivalent DNA vaccine targeting ROP6, and MIC12 for protection against acute (RH strain) and chronic (PRU strain) toxoplasmosis in mouse models.MethodsEukaryoti...

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Tallennettuna:
Päätekijät: Bohuai Xu, Yue Bi, Yaowen Wang, Jie Sun, Jia Chen, Jingqi Mu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2025-11-01
Sarja:Frontiers in Veterinary Science
Aiheet:
Toxoplasma gondii
toxoplasmosis
DNA vaccine
TgROP6
TgMIC12
Linkit:https://www.frontiersin.org/articles/10.3389/fvets.2025.1674435/full
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