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Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol

Oxidized LDL (OxLDL) is composed of many potentially proatherogenic molecules, including oxysterols. Of the oxysterols, 7-ketocholesterol (7-KC) is found in relatively large abundance in OxLDL, as well as in atherosclerotic plaque and foam cells in vivo. Although there is evidence that 7-KC activate...

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Hlavní autoři: John M. Hayden, Libuse Brachova, Karen Higgins, Lewis Obermiller, Alex Sevanian, Srikrishna Khandrika, Peter D. Reaven
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2002-01-01
Edice:Journal of Lipid Research
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S0022227520301838
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