Engineering hypercompact IscB nucleases for efficient and versatile genome editing in rice
Abstract Background IscB (Insertion sequences Cas9-like OrfB) represents a novel class of RNA-guided nucleases, approximately one-third the size of Cas9 proteins. Despite the limited natural efficiency in eukaryotic cells, recent advances have led to the engineering of several IscBs for mammalian ge...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BMC
2026-01-01
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| Σειρά: | Genome Biology |
| Θέματα: | |
| Διαθέσιμο Online: | https://doi.org/10.1186/s13059-026-03953-y |
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