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Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes

Summary: The eukaryotic BBSome is a transport complex within cilia and assembled by chaperonin-like BBS proteins. Recent work indicates nuclear functions for BBS proteins in mammals, but it is unclear how common these are in extant proteins or when they evolved. We screened for BBS orthologues acros...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Alexander Ewerling, Vanessa Maissl, Bill Wickstead, Helen Louise May-Simera
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2023-04-01
Schriftenreihe:iScience
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S258900422300487X
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