Multitrait GWAS of non-suicidal self-injury and the polygenetic effects on child psychopathology and brain structures

Summary: Non-suicidal self-injury (NSSI) is highly prevalent in recent years, but the genetic architecture remains unknown. We perform a multitrait analysis of genome-wide association study on NSSI, incorporating self-harm and suicide attempt. Common genetic variants account for 6.03% of NSSI varian...

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Principais autores:	Yaoyao Sun, Guorui Zhao, Yuyanan Zhang, Zhe Lu, Zhewei Kang, Junyuan Sun, Xiaoyang Feng, Jing Guo, Yundan Liao, Liangkun Guo, Yang Yang, Dai Zhang, Wenjian Bi, Runsen Chen, Weihua Yue
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-05-01
Serija:	Cell Reports Medicine
Teme:	non-suicidal self-injury genome-wide association analysis polygenic risk score brain imaging lifestyle adolescent
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2666379125001922
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