MiR-574-3p inhibits glucose toxicity-induced pancreatic β-cell dysfunction by suppressing PRMT1

Abstract Background Pancreatic β-cell dysfunction is commonly observed in patients with type 2 diabetes mellitus. Protein arginine methyltransferase 1 (PRMT1) plays an important role in pancreatic β-cell dysfunction. However, the detailed mechanisms remain largely unknown. Methods RT-qPCR, western b...

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Autors principals:	Lixia Lv, Xiumin Wang, Jinhua Shen, Ying Cao, Qin Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-07-01
Col·lecció:	Diabetology & Metabolic Syndrome
Matèries:	miR-574-3p PRMT1 Proliferation Apoptosis Insulin secretion
Accés en línia:	https://doi.org/10.1186/s13098-022-00869-y
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