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Proteolytic Cleavages in the VEGF Family: Generating Diversity among Angiogenic VEGFs, Essential for the Activation of Lymphangiogenic VEGFs

Specific proteolytic cleavages turn on, modify, or turn off the activity of vascular endothelial growth factors (VEGFs). Proteolysis is most prominent among the lymph­angiogenic VEGF-C and VEGF-D, which are synthesized as precursors that need to undergo enzymatic removal of their C- and N-terminal p...

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Guardado en:
Autores principales: Jaana Künnapuu, Honey Bokharaie, Michael Jeltsch
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2021-02-01
Colección:Biology
Materias:
vascular endothelial growth factors (VEGFs)
VEGF-A
PlGF
VEGF-B
VEGF-C
VEGF-D
Acceso en línea:https://www.mdpi.com/2079-7737/10/2/167
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