Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis.

Aspergillus fumigatus (Af) is a major mould pathogen found ubiquitously in the air. It commonly infects the airways of people with cystic fibrosis (CF) leading to Aspergillus bronchitis or allergic bronchopulmonary aspergillosis. Resident alveolar macrophages and recruited neutrophils are important...

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Principais autores:	Amelia Bercusson, Thomas J Williams, Nicholas J Simmonds, Eric Wfw Alton, Uta Griesenbach, Anand Shah, Adilia Warris, Darius Armstrong-James
格式:	Artigo
语言:	Inglês
出版:	Public Library of Science (PLoS) 2025-02-01
丛编:	PLoS Pathogens
在线阅读:	https://doi.org/10.1371/journal.ppat.1012784
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