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Haptoglobin gene polymorphisms and interleukin-6 and -8 levels in patients with sickle cell anemia

BACKGROUND: Haptoglobin genotypes, and interleukin-6 and -8 participate in the pathophysiology of sickle cell anemia. The expression of cytokines is regulated by genetic mechanisms however the effect of haptoglobin polymorphisms on these cytokines is not fully understood. This study aimed to compare...

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Principais autores: Bruna Spinella Pierrot-Gallo, Perla Vicari, Sandra Satiko Matsuda, Samuel Ademola Adegoke, Grazielle Mecabo, Maria Stella Figueiredo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015-10-01
Serier:Revista Brasileira de Hematologia e Hemoterapia
Fag:
Haptoglobin polymorphism
Genotype
Interleukins
Sickle cell anemia
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842015000500329&lng=en&tlng=en
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