Insights into anti-tumor immunity via the polyomavirus shared across human Merkel cell carcinomas

Understanding and augmenting cancer-specific immunity is impeded by the fact that most tumors are driven by patient-specific mutations that encode unique antigenic epitopes. The shared antigens in virus-driven tumors can help overcome this limitation. Merkel cell carcinoma (MCC) is a particularly in...

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Autores principales:	Saumya Jani, Candice D. Church, Paul Nghiem
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2023-05-01
Colección:	Frontiers in Immunology
Materias:	Merkel cell carcinoma Merkel cell polyomavirus skin cancer anti-tumor T cells immunotherapy oncoproteins
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172913/full
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