Array-based Identification of Copy Number Changes in a Diagnostic Setting : Simultaneous gene-focused and low resolution whole human genome analysis

Objectives: The aim of this study was to develop and validate a comparative genomic hybridisation (CGH) array that would allow simultaneous targeted analysis of a panel of disease genes and low resolution whole genome analysis. Methods: A bespoke Roche NimbleGen 12x135K CGH array (Roche NimbleGen In...

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Hauptverfasser:	Renate Marquis-Nicholson, Elaine Doherty, Jennifer M. Love, Chuan-Ching Lan, Alice M. George, Anthony Thrush, Donald R. Love
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Sultan Qaboos University 2013-02-01
Schriftenreihe:	Sultan Qaboos University Medical Journal
Schlagworte:	array comparative genomic hybridization (acgh) gene dosage copy number variants (cnvs) dna microarray molecular diagnosis.
Online-Zugang:	https://journals.squ.edu.om/index.php/squmj/article/view/1745
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