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Courtship and distress ultrasonic vocalizations are altered in a mouse model of Angelman syndrome

Abstract Background Angelman syndrome (AS) is a single-gene neurodevelopmental disorder caused by loss of function of the maternal copy of the UBE3A gene. Nearly all individuals with AS lack speech, resulting in major impacts on daily life for patients and caregivers. To evaluate new therapies for A...

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Autores principales: Caleigh D. Guoynes, Grace Pavalko, Michael S. Sidorov
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2025-10-01
Colección:Journal of Neurodevelopmental Disorders
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Acceso en línea:https://doi.org/10.1186/s11689-025-09648-y
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