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The –514 polymorphism in the hepatic lipase gene (LIPC) does not influence androgen-mediated stimulation of hepatic lipase activity

The –514T allele of hepatic lipase is associated with increased high density lipoprotein-cholesterol levels in men, but not in women. This observation suggests that the –514C to T polymorphism may diminish the response of hepatic lipase to androgens. To test this hypothesis, five –514T and five –514...

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Auteurs principaux: Gloria Lena Vega, Jimin Gao, Thomas P. Bersot, Robert W. Mahley, Richard Verstraete, Scott M. Grundy, Ann White, Jonathan C. Cohen
Format: Artigo
Langue:Inglês
Publié: Elsevier 1998-07-01
Collection:Journal of Lipid Research
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S0022227520325347
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