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CAR T-cells for T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) has a dismal prognosis in case of relapsed or refractory disease. Contrary to B-ALL, few immunotherapies are available for T-ALL. Use of autologous CAR T-cells is challenging due to shared antigen between leukemic and normal T-cells responsible for fratric...

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Bibliografiske detaljer
Principais autores: Marie Emilie Dourthe, André Baruchel
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-06-01
Serier:EJC Paediatric Oncology
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S2772610X24000096
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