Inhibition of IL-17A in tumor microenvironment augments cytotoxicity of tumor-infiltrating lymphocytes in tumor-bearing mice.

It remains controversial whether IL-17A promotes or inhibits cancer progression. We hypothesized that IL-17A that is locally produced in the tumor microenvironment has an important role in angiogenesis and tumor immunity. We investigated the effect of inhibiting IL-17A at tumor sites on tumor growth...

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Detalhes bibliográficos

Principais autores:	Keiji Hayata, Makoto Iwahashi, Toshiyasu Ojima, Masahiro Katsuda, Takeshi Iida, Mikihito Nakamori, Kentaro Ueda, Masaki Nakamura, Motoki Miyazawa, Toshiaki Tsuji, Hiroki Yamaue
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2013-01-01
Colecção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3556079?pdf=render
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