Acquisition of durable insulin-producing cells from human adipose tissue-derived mesenchymal stem cells as a foundation for cell- based therapy of diabetes mellitus

Abstract This study aimed to identify the suitable induction protocol to produce highly qualified insulin producing cells (IPCs) from human adipose tissue derived stem cells (ADSCs) and evaluate the efficacy of the most functionally IPCs in management of diabetes mellitus (DM) in rats. The ADSCs wer...

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主要な著者:	Ghada Nour Eldeen, Hadeer A. Aglan, Nadia S. Mahmoud, Mazen Abdel Rasheed, Osama M. Azmy, Hanaa H. Ahmed
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2024-10-01
シリーズ:	Scientific Reports
主題:	Human adipose tissue derived stem cells Laminin–coated plates with extrinsic factors Insulin- producing cells In vitro assessment In vivo study
オンライン･アクセス:	https://doi.org/10.1038/s41598-024-74527-w
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