A study of N-acetyltransferase 2 gene polymorphisms in the Indian population and its relationship with serum isoniazid concentrations in a cohort of tuberculosis patients

The N-acetyltransferase 2 (NAT2) gene exhibits substantial genetic diversity, leading to distinct acetylator phenotypes among individuals. In this study, we determine NAT2 gene polymorphisms in tuberculosis (TB) patients and analyze serum isoniazid (INH) concentrations across the various genotypes....

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Główni autorzy:	Renuka Munshi, Falguni Panchal, Unnati Desai, Ketaki Utpat, Kirti Rajoria
Format:	Artigo
Język:	Inglês
Wydane:	PAGEPress Publications 2024-12-01
Seria:	Monaldi Archives for Chest Disease
Hasła przedmiotowe:	Tuberculosis serum isoniazid concentrations NAT2 genetic polymorphisms adverse drug reactions drug-induced hepatotoxicity
Dostęp online:	https://www.monaldi-archives.org/macd/article/view/3181
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