Friedländer-Type Reaction of 4-Cholesten-3-one with 2′-Aminoacetophenone: Angular versus Linear Quinoline-Fused Steroids

To optimize the experimental conditions used for the Friedländer-type condensation, an angular fused 4-substituted quinoline steroid has been obtained in very high yield and regioselectivity using readily available 4-cholesten-3-one and 2′-aminoacetophenone. Moreover, by varying the reaction conditi...

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Principais autores:	Caterina Momoli, Valerio Morlacci, Marco Chiarini, Laura Palombi, Antonio Arcadi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-08-01
coleção:	Molbank
Assuntos:	fused steroid quinoline polycycles Friedlӓnder’s condensation angular cholestanoquinoline linear cholestanoquinoline
Acesso em linha:	https://www.mdpi.com/1422-8599/2023/3/M1712
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