A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer

Abstract Background This phase Ib study (NCT00960960) evaluated pictilisib (GDC-0941; pan-phosphatidylinositol 3-kinase inhibitor) plus paclitaxel, with and without bevacizumab or trastuzumab, or in combination with letrozole, in patients with locally recurrent or metastatic breast cancer. Methods T...

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Detalhes bibliográficos

Principais autores:	Patrick Schöffski, Sara Cresta, Ingrid A. Mayer, Hans Wildiers, Silvia Damian, Steven Gendreau, Isabelle Rooney, Kari M. Morrissey, Jill M. Spoerke, Vivian W. Ng, Stina M. Singel, Eric Winer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-09-01
Colecção:	Breast Cancer Research
Assuntos:	Pictilisib GDC-0941 PI3K
Acesso em linha:	http://link.springer.com/article/10.1186/s13058-018-1015-x
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