Identification of altered salivary microRNAs in Cavalier King Charles Spaniels affected by mitral valve disease at different ACVIM stages

Abstract Myxomatous mitral valve disease (MMVD) in Cavalier King Charles Spaniels (CKCSs) can be diagnosed at a young age. Early and sensitive biomarkers related to the disease are currently lacking. MicroRNAs (miRNAs) are involved in the onset and progression of canine MMVD. This study aimed to pro...

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Autores principales:	Sara Ghilardi, Gaspare Salvi, Mara Bagardi, Ombretta Balbi, Asia Balgera, Yasmine Dadi, Giovanni Romito, Michele Polli, Maddalena Arigoni, Raffaele Calogero, Paola G. Brambilla, Cristina Lecchi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2026-02-01
Colección:	Scientific Reports
Materias:	Myxomatous mitral valve disease microRNA Saliva Biomarkers Dog Cavalier King Charles Spaniels
Acceso en línea:	https://doi.org/10.1038/s41598-026-38660-y
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