FluoroTensor: Identification and tracking of colocalised molecules and their stoichiometries in multi-colour single molecule imaging via deep learning

The identification of photobleaching steps in single molecule fluorescence imaging is a well-established procedure for analysing the stoichiometries of molecular complexes. Nonetheless, the method is challenging with protein fluorophores because of the high levels of noise, rapid bleaching and highl...

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Autori principali:	Max F.K. Wills, Carlos Bueno Alejo, Nikolas Hundt, Andrew J. Hudson, Ian C. Eperon
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Association for the Advancement of Science (AAAS) 2024-12-01
Serie:	Computational and Structural Biotechnology Journal
Soggetti:	Single molecule imaging Colocalisation Stoichiometries of protein fluorophores Convolutional neural networks Single particle tracking Diffusion parameters
Accesso online:	http://www.sciencedirect.com/science/article/pii/S200103702400028X
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