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P042 | PU.1 as master regulator of acute myeloid leukemia venetoclax resistance

Introduction. Venetoclax-based therapies have improved outcomes in acute myeloid leukemia (AML), especially in elderly or unfit patients. However, resistance remains a major limitation. Recent studies suggest that monocytic differentiation (FAB M4/M5) is associated with reduced venetoclax sensitivi...

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Autore principale: Alessandro Ferrando
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2026-03-01
Serie:Haematologica
Accesso online:https://haematologica.org/article/view/13306
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