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Examining transfer of TERT to mitochondria under oxidative stress

Abstract The primary role of telomerase is the lengthening of telomeres. Nonetheless, emerging evidence highlights additional functions of telomerase outside of the nucleus. Specifically, its catalytic subunit, TERT (Telomerase Reverse Transcriptase), is detected in the cytosol and mitochondria. Sev...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Dmitrii Burkatovskii, Andrey Bogorodskiy, Ivan Maslov, Olga Moiseeva, Roman Chuprov-Netochin, Ekaterina Smirnova, Nikolay Ilyinsky, Alexey Mishin, Sergey Leonov, Georg Bueldt, Valentin Gordeliy, Thomas Gensch, Valentin Borshchevskiy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-10-01
Schriftenreihe:Scientific Reports
Schlagworte:
TERT
Protein transport
Mitochondria
Oxidative stress
SNAP-tag
Online-Zugang:https://doi.org/10.1038/s41598-024-75127-4
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