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Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya

Asgard archaea include the closest known archaeal relatives of eukaryotes. Here, the authors provide evidence that eukaryotic and Asgard thymidylate synthases (required for DNA synthesis) may have a bacterial origin, and additional lateral transfer of bacterial genes may have shaped the metabolism o...

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Autors principals: Jonathan Filée, Hubert F. Becker, Lucille Mellottee, Rima Zein Eddine, Zhihui Li, Wenlu Yin, Jean-Christophe Lambry, Ursula Liebl, Hannu Myllykallio
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2023-02-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-023-36487-z
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