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Modulation of CXC Chemokine Receptor Expression and Function in Human Neutrophils during Aging In Vitro Suggests a Role in Their Clearance from Circulation

In mice, differential regulation of CXC chemokine receptor expression in circulating polymorphonuclear neutrophils (PMNs) undergoing senescence results in homing to the bone marrow. However, the role of this compartment and of the chemokine receptor CXCR4 is still under discussion, and only scarce d...

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Autori principali: Katja C. Weisel, Frank Bautz, Gabriele Seitz, Sedat Yildirim, Lothar Kanz, Robert Möhle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2009-01-01
Serie:Mediators of Inflammation
Accesso online:http://dx.doi.org/10.1155/2009/790174
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