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Calpain-1 weakens the nuclear envelope and promotes the release of neutrophil extracellular traps

Abstract The inducers of neutrophil extracellular trap (NET) formation are heterogeneous and consequently, there is no specific pathway or signature molecule indispensable for NET formation. But certain events such as histone modification, chromatin decondensation, nuclear envelope breakdown, and NE...

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Principais autores: Jeeshan Singh, Leticija Zlatar, Marco Muñoz-Becerra, Günter Lochnit, Irmgard Herrmann, Felix Pfister, Christina Janko, Jasmin Knopf, Moritz Leppkes, Janina Schoen, Luis E. Muñoz, Georg Schett, Martin Herrmann, Christine Schauer, Aparna Mahajan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-09-01
coleção:Cell Communication and Signaling
Assuntos:
Nesprin-1
Calpain-1
Neutrophil extracellular traps (NETs)
Nuclear envelope break down
Acesso em linha:https://doi.org/10.1186/s12964-024-01785-6
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