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5FU/Oxaliplatin-Induced Jagged1 Cleavage Counteracts Apoptosis Induction in Colorectal Cancer: A Novel Mechanism of Intrinsic Drug Resistance

Colorectal cancer (CRC) is characterized by early metastasis, resistance to anti-cancer therapy, and high mortality rate. Despite considerable progress in the development of new treatment options that improved survival benefits in patients with early-stage or advanced CRC, many patients relapse due...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Maria Pelullo, Sabrina Zema, Mariangela De Carolis, Samantha Cialfi, Maria Valeria Giuli, Rocco Palermo, Carlo Capalbo, Giuseppe Giannini, Isabella Screpanti, Saula Checquolo, Diana Bellavia
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2022-07-01
Rangatū:Frontiers in Oncology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fonc.2022.918763/full
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