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Determining the Lowest Optimally Effective Methotrexate Dose for Individual RA Patients Using Their Dose Response Relation in a Tight Control Treatment Approach.

OBJECTIVE:To determine the optimal methotrexate dose in individual patients and to explore whether this optimal dose and the level of disease activity at that dose could be predicted. METHODS:Data from CAMERA II trial comparing MTX and MTX with 10 mg of prednisone both in a tight control treatment s...

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Autors principals: Sandhya C Nair, Johannes W G Jacobs, Marije F Bakker, Z Nazira Jahangier, Johannes W J Bijlsma, Jacobs M van Laar, Floris P J G Lafeber, Paco M J Welsing, Utrecht Arthritis Cohort Study Group
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2016-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4795693?pdf=render
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