Revealing Spatial and Temporal Patterns of Cell Death, Glial Proliferation, and Blood-Brain Barrier Dysfunction Around Implanted Intracortical Neural Interfaces

Improving the long-term performance of neural electrode interfaces requires overcoming severe biological reactions such as neuronal cell death, glial cell activation, and vascular damage in the presence of implanted intracortical devices. Past studies traditionally observe neurons, microglia, astroc...

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Autores principales:	Steven M. Wellman, Lehong Li, Yalikun Yaxiaer, Ingrid McNamara, Takashi D. Y. Kozai
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2019-05-01
Colección:	Frontiers in Neuroscience
Materias:	oligodendrocytes NG2 glia pericytes tissue-electrode interface neurodegeneration gliosis
Acceso en línea:	https://www.frontiersin.org/article/10.3389/fnins.2019.00493/full
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