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Population pharmacokinetic modeling to facilitate dose selection of tapentadol in the pediatric population

Estelle Watson,1 Akash Khandelwal,1 Jan Freijer,1 John van den Anker,2,3 Claudia Lefeber,1 Mariëlle Eerdekens1 1Grünenthal GmbH, Aachen, Germany; 2Division of Paediatric Pharmacology and Pharmacometrics, University of Basel Children’s Hospital, Basel, Switzerland; 3Division of Clinic...

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Principais autores: Watson E, Khandelwal A, Freijer J, van den Anker J, Lefeber C, Eerdekens M
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2019-10-01
Serier:Journal of Pain Research
Fag:
Tapentadol
pediatric
pain management
dosing
nonlinear mixed effects modeling
Online adgang:https://www.dovepress.com/population-pharmacokinetic-modeling-to-facilitate-dose-selection-of-ta-peer-reviewed-article-JPR
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