Engineered neutrophil membrane nanosystem for targeted siRNA therapy in myocardial ischemia–reperfusion injury

Abstract Despite the widespread use of emergency coronary reperfusion therapy, effectively managing reperfusion-induced myocardial injury remains a major clinical challenge. Neutrophil infiltration and the release of damage-associated molecular patterns (DAMPs), particularly the alarmin S100A8/A9, p...

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Autori principali:	Yaohui Jiang, Zhe Wang, Penglei Chen, He Lu, Xiaoxu Tian, Pin Jiang, Rui Luo, Yujing Zhou, Zhikang Lv, Wenjun Mao, Shuai Ren, Xiaocheng Wang, Haiqiang Sang, Wei Yang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-12-01
Serie:	Journal of Nanobiotechnology
Soggetti:	Myocardial ischemia/reperfusion injury S100A8/A9 siRNA Neutrophil membrane Coated Nanoparticles
Accesso online:	https://doi.org/10.1186/s12951-025-03965-z
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