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Synthesis of Novel Shikonin Derivatives and Pharmacological Effects of Cyclopropylacetylshikonin on Melanoma Cells

Despite much research in the last centuries, treatment of malignant melanoma is still challenging because of its mostly unnoticeable metastatic spreading and aggressive growth rate. Therefore, the discovery of novel drug leads is an important goal. In a previous study, we have isolated several shiko...

Celý popis

Uloženo v:
Hlavní autoři: Christin Durchschein, Antje Hufner, Beate Rinner, Alexander Stallinger, Alexander Deutsch, Birgit Lohberger, Rudolf Bauer, Nadine Kretschmer
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2018-10-01
Edice:Molecules
Témata:
shikonin derivatives
cyclopropylacetylshikonin
apoptosis
melanoma
On-line přístup:https://www.mdpi.com/1420-3049/23/11/2820
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