Liver‐Secreted Extracellular Vesicles Promote Cirrhosis‐Associated Skeletal Muscle Injury Through mtDNA‐cGAS/STING Axis

Abstract Skeletal muscle atrophy (sarcopenia) is a serious complication of liver cirrhosis, and chronic muscle inflammation plays a pivotal role in its pathologenesis. However, the detailed mechanism through which injured liver tissues mediate skeletal muscle inflammatory injury remains elusive. Her...

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Principais autores:	Xiaoli Fan, Yunke Peng, Bo Li, Xiaoze Wang, Yifeng Liu, Yi Shen, Guofeng Liu, Yanyi Zheng, Qiaoyu Deng, Jingping Liu, Li Yang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2025-03-01
Series:	Advanced Science
Assuntos:	cGAS‐STING extracellular vesicles liver fibrosis mtDNA skeletal muscle atrophy
Acceso en liña:	https://doi.org/10.1002/advs.202410439
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