Activation of GSDME by Lithospermum erythrorhizon drives pyroptotic cell death

Objective: To reveal GSDME-executed pyroptosis in cancer cells induced by the Chinese traditional herbal medicine plant Lithospermum erythrorhizon (L. erythrorhizon, Zi Cao) and to investigate the potential mechanism. Methods: L. erythrorhizon was extracted by ultrasonication in 95% ethanol, and det...

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Auteurs principaux:	Sanjiao Wang, Zhaoheng Liu, Jiajian Guo, Yunqian Li, Yue Zhang, Mingrui Yang, Guoqi Niu, Wenfu Ma
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2023-07-01
Collection:	Journal of Traditional Chinese Medical Sciences
Sujets:	Lithospermum erythrorhizon Pyroptosis GSDME Anti-tumor activity
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2095754823000388
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