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Improvement on Permeability of Cyclic Peptide/Peptidomimetic: Backbone <i>N</i>-Methylation as A Useful Tool

Peptides have a three-dimensional configuration that can adopt particular conformations for binding to proteins, which are well suited to interact with larger contact surface areas on target proteins. However, low cell permeability is a major challenge in the development of peptide-related drugs. In...

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Autors principals: Yang Li, Wang Li, Zhengshuang Xu
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2021-05-01
Col·lecció:Marine Drugs
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Accés en línia:https://www.mdpi.com/1660-3397/19/6/311
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