Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels

Tongmai Yangxin (TMYX) is a complex compound of the Traditional Chinese Medicine (TCM) used to treat several cardiac rhythm disorders; however, no information regarding its mechanism of action is available. In this study we provide a detailed characterization of the effects of TMYX on the electrical...

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Hlavní autoři:	Chiara Piantoni, Manuel Paina, David Molla, Sheng Liu, Giorgia Bertoli, Hongmei Jiang, Yanyan Wang, Yi Wang, Dario DiFrancesco, Andrea Barbuti, Annalisa Bucchi, Mirko Baruscotti
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2022-03-01
Edice:	eLife
Témata:	pacemaker current sinoatrial node TMYX pure bradycardic agents cAMP antagonism HCN channels
On-line přístup:	https://elifesciences.org/articles/75119
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