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Serum-Free Medium for Recombinant Protein Expression in Chinese Hamster Ovary Cells

At present, nearly 70% of recombinant therapeutic proteins (RTPs) are produced by Chinese hamster ovary (CHO) cells, and serum-free medium (SFM) is necessary for their culture to produce RTPs. In this review, the history and key components of SFM are first summarized, and its preparation and experim...

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Autors principals: Weifeng Li, Zhenlin Fan, Yan Lin, Tian-Yun Wang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021-03-01
Col·lecció:Frontiers in Bioengineering and Biotechnology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fbioe.2021.646363/full
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