Integrative transcriptomic analysis reveals cross-species conserved core genes and pathways in alveolar macrophages during ALI/ARDS

Abstract Background and purpose acute respiratory distress syndrome (ARDS) is a severe pulmonary condition characterized by alveolar-capillary damage and refractory hypoxemia. Alveolar macrophages (AMs) play a crucial role in regulating inflammation and repair processes during acute lung injury (ALI...

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Principais autores:	Aguo Li, Kenqi Zhang, Hongyan Wang, Jianhua Li, Yeping Yao, Yong-Sheng Tu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-10-01
coleção:	BMC Pulmonary Medicine
Assuntos:	Acute lung injury Alveolar macrophages Transcriptome sequencing Bioinformatics analysis Efferocytosis
Acesso em linha:	https://doi.org/10.1186/s12890-025-03928-y
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