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Lung Mast Cells Have a High Constitutive Expression of Carboxypeptidase A3 mRNA That Is Independent from Granule-Stored CPA3

The mast cell granule metalloprotease CPA3 is proposed to have important tissue homeostatic functions. However, the basal CPA3 mRNA and protein expression among mast cell populations has remained poorly investigated. Using a novel histology-based methodology that yields quantitative data on mRNA and...

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Principais autores: Premkumar Siddhuraj, Carl-Magnus Clausson, Caroline Sanden, Manar Alyamani, Mohammad Kadivar, Jan Marsal, Joanna Wallengren, Leif Bjermer, Jonas S. Erjefält
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-02-01
coleção:Cells
Assuntos:
mast cells
carboxypeptidase A3
lung
gut
skin
chymase
Acesso em linha:https://www.mdpi.com/2073-4409/10/2/309
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