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Innovative spectrophotometric methods for the analysis of terbinafine and ketoconazole in pharmaceutical preparations with compliance to greenness and blueness metrics

Abstract Five simple, sensitive, and eco-friendly spectrophotometric techniques were developed for solving the highly overlapped spectra of Terbinafine HCl and Ketoconazole in their combined tablet formulation, for the first time without the common excipients interfering. The methods included third...

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Principais autores: Engy Attaa Bakr, Abdallah M. Zeid, Shereen M. Shalan, Yasser El-Shabrawy, Aya Saad Radwan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2025-11-01
Series:Scientific Reports
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Acceso en liña:https://doi.org/10.1038/s41598-025-25067-4
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