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Exosomes derived from platelet-rich plasma present a novel potential in alleviating knee osteoarthritis by promoting proliferation and inhibiting apoptosis of chondrocyte via Wnt/β-catenin signaling pathway

Abstract Background Platelet-rich plasma (PRP) provides a nonsurgical approach for treating osteoarthritis (OA). Exosomes that play vital roles in intercellular communication have been studied extensively. Here, we investigated the therapeutic potential and molecular mechanism of exosomes derived fr...

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Principais autores: Xuchang Liu, Lubo Wang, Chengshan Ma, Guozong Wang, Yuanji Zhang, Shui Sun
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2019-12-01
Series:Journal of Orthopaedic Surgery and Research
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Acceso en liña:https://doi.org/10.1186/s13018-019-1529-7
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