Rebamipide ameliorates atherosclerosis by controlling lipid metabolism and inflammation.
The oral administration of rebamipide decreased plaque formation in atherosclerotic lesions as well as the markers of metabolic disorder in ApoE-deficient mice with atherosclerosis. Pro-inflammatory cytokines were also suppressed by rebamapide. In addition, the population of Th17 was decreased, wher...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2017-01-01
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| Schriftenreihe: | PLoS ONE |
| Online-Zugang: | http://europepmc.org/articles/PMC5328247?pdf=render |
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