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Region-Specific Roles of TGF-β2 and Angiotensin II in Fibrotic and Inflammatory Remodeling of the Optic Nerve Head

This study investigated the region-specific roles of transforming growth factor-β2 (TGF-β2) and angiotensin II (AngII) in extracellular matrix (ECM) remodeling and inflammatory responses within scleral tissues surrounding the optic nerve head (ONH), using primary human fibroblasts from posterior scl...

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Autori principali: Si-Eun Oh, Jie-Hyun Kim, Se-Eun Park, Chan-Kee Park, Hae-Young Lopilly Park
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2025-11-01
Serie:Cells
Soggetti:
glaucoma
optic nerve head
TGF-β2
angiotensin II
extracellular matrix remodeling
neuroinflammation
Accesso online:https://www.mdpi.com/2073-4409/14/22/1830
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