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Complete Response to Pembrolizumab in a Patient with Castration-Resistant Prostate Cancer with Both BRCA Positivity and a High Frequency of Microsatellite Instability: A Case Report

Introduction: There have been few reports of patients for whom a cancer gene panel test for solid tumors revealed the simultaneous presence of BRCA mutation and microsatellite instability (MSI)-high status. BRCA mutations have been reported in 13% of castration-resistant prostate cancer (CRPC) patie...

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Furkejuvvon:
Váldodahkkit: Takayuki Hirano, Kousuke Yonezawa, Takashi Kawahara, Nobuhiko Mizuno, Hiroyuki Hayashi, Yuta Karibe, Jun Asano, Shusei Fusayasu, Kazuhide Makiyama, Hiroji Uemura, Junichi Ohta, Masatoshi Moriyama
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Karger Publishers 2024-08-01
Ráidu:Case Reports in Oncology
Fáttát:
case report
pembrolizumab
microsatellite instability
castration-resistant prostate cancer
Liŋkkat:https://beta.karger.com/Article/FullText/540419
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