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Formulation and optimization of self-nanoemulsifying drug delivery systems (SNEDDS) for enhancing the solubility, bioavailability, and anticancer activity of flutamide

Abstract Low bioavailability remains a challenge for poorly water-soluble drugs like flutamide, a key therapeutic agent for prostate cancer. To address this, Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) were formulated to enhance solubility, absorption, and therapeutic efficacy. SNEDDS improv...

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Autores principales: Kavita Sapra, Rupali Sharma, Suman Samaddar, Satish Sardana
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Nature 2026-01-01
Colección:Discover Pharmaceutical Sciences
Materias:
Flutamide
SNEDDS
Prostate cancer
Bioavailability
Solubility
Cytotoxicity
Acceso en línea:https://doi.org/10.1007/s44395-026-00037-5
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