R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.

Friedreich ataxia (FRDA) and Fragile X syndrome (FXS) are among 40 diseases associated with expansion of repeated sequences (TREDs). Although their molecular pathology is not well understood, formation of repressive chromatin and unusual DNA structures over repeat regions were proposed to play a rol...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Matthias Groh, Michele M P Lufino, Richard Wade-Martins, Natalia Gromak
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Public Library of Science (PLoS) 2014-05-01
Ráidu:	PLoS Genetics
Liŋkkat:	https://doi.org/10.1371/journal.pgen.1004318
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!