Molecular underpinnings of dedifferentiation and aggressiveness in chromophobe renal cell carcinoma

Sarcomatoid dedifferentiation is common to multiple renal cell carcinoma (RCC) subtypes, including chromophobe RCC (ChRCC), and is associated with increased aggressiveness, resistance to targeted therapies, and heightened sensitivity to immunotherapy. To study ChRCC dedifferentiation, we performed m...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Payal Kapur, Hua Zhong, Daniel Le, Ratna Mukhopadhyay, Jeffrey Miyata, Deyssy Carrillo, Dinesh Rakheja, Satwik Rajaram, Steffen Durinck, Zora Modrusan, James Brugarolas
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical investigation 2024-05-01
Σειρά:	JCI Insight
Θέματα:	Oncology
Διαθέσιμο Online:	https://doi.org/10.1172/jci.insight.176743
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