The rise of rat models for Duchenne muscular dystrophy and therapeutic evaluations

Abstract Duchenne muscular dystrophy (DMD) is a devastating X-linked neuromuscular disorder characterized by the absence of a functional dystrophin, leading to progressive muscle loss responsible for cardiorespiratory failure and premature death. While mouse, dog, and pig models have long supported...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Frederic Relaix, Peggy Lafuste, Valentina Taglietti, Laurent Tiret
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-09-01
Цуврал:	Skeletal Muscle
Нөхцлүүд:	DMD mutations Becker Muscular Dystrophy Rodent models Dystrophin isoforms Preclinical modeling Myonecrosis
Онлайн хандалт:	https://doi.org/10.1186/s13395-025-00395-1
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!