Synthesis of 4-morpholino-5,8,9,10-tetrahydropyrimido[4,5–b]quinolin-6(7H)-one derivatives and in silico-in vitro evaluation of their antimalarial activity

A novel series of 4-morpholino-5,8,9,10-tetrahydropyrimido[4,5–b]quinolin-6(7H)-one has been synthesized by an extremely effective, straightforward and clean methodology for one-pot multicomponent condensation reaction (MCRs) utilizing polyphosphoric acid as a catalyst in conjunction with acetic aci...

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Detalles Bibliográficos

Principais autores:	Pratik Patel, Bhavin Patel, Megha Patel, Paresh Patel
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2024-01-01
Series:	Results in Chemistry
Assuntos:	Morpholine Pyrimido[4,5–b]quinoline Antimalarial agents Plasmodium falciparum
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2211715624000730
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